Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531465 | 1.00 | CYP2C9 (0.68) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL13241355 | 1.00 | CYP2C9 (0.68) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL17917465 | 0.84 | CYP2C9 (0.55) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL11860615 | 0.83 | CYP2C9 (0.48) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL10972589 | 0.81 | CYP2C9 (0.66) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL3735404 | 0.78 | CYP2C9 (0.61) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL3735405 | 0.78 | CYP2C9 (0.61) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL29558213 | 0.78 | CYP2C9 (0.61) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL11857939 | 0.77 | CYP2C9 (0.41) | CYP2C9ALDH1A1POLBMPINPC1 | |
| SCHEMBL239325 | 0.77 | CYP2C9 (0.59) | CYP2C9MAPTLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002826-B1 | NOVEL PHOSPHORAMIDOTHIOATE DERIVATIVES, PESTICIDAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR PREPARING THE NOVEL DERIVATIVES AND THE USE OF THE NOVEL DERIVATIVES FOR COMBATING PESTS | ROHM AND HAAS COMPANY (US) | 1983-06-01 | — | — | EP | disclosed |
| US-4263288-A | Acaricidal, insecticidal, and nematocidal phosphoramidothioates | ROHM AND HAAS COMPANY (US) | 1981-04-21 | — | — | US | disclosed |
| EP-0002826-A1 | Novel phosphoramidothioate derivatives, pesticidal compositions containing them, processes for preparing the novel derivatives and the use of the novel derivatives for combating pests | ROHM AND HAAS COMPANY (US) | 1979-07-11 | — | — | EP | disclosed |
| US-4134913-A | MITICIDES | THE UPJOHN COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4066765-A | Arthropodicidal formamidines | THE UPJOHN COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-3998969-A | Formamidine insecticides | THE UPJOHN COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
| US-3954997-A | MITICIDES, INSECTICIDES | THE UPJOHN COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3947591-A | Pesticidal N,N\"-thio and dithio bis(substituted phenyl formamidines) | THE UPJOHN COMPANY (US) | 1976-03-30 | — | — | US | disclosed |