Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210021 | 0.84 | CYP2C9 (0.68) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL11531465 | 0.84 | CYP2C9 (0.68) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL13241355 | 0.84 | CYP2C9 (0.68) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL16479735 | 0.72 | CYP2C9 (0.52) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL10972589 | 0.71 | CYP2C9 (0.66) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL29472028 | 0.71 | CYP2C9 (0.59) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL239325 | 0.71 | CYP2C9 (0.59) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL239326 | 0.71 | CYP2C9 (0.59) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL11860615 | 0.69 | CYP2C9 (0.48) | CYP2C9MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL9336284 | 0.69 | CYP2C9 (0.57) | CYP2C9MAPTLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |
| US-20160200674-A1 | IDO INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200674-A1 | IDO INHIBITORS | IDO1, IDO2, INMT | CYP2C9 1489/4885MAPT 2351/4885LMNA 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.