Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28329595 | 0.94 | CYP2D6 (0.57) | CYP2D6SMN1; SMN2KEAP1NFE2L2LMNA | |
| SCHEMBL6884698 | 0.85 | AKR1C3 (0.51) | CYP2D6ACHEALOX5ALDH1A1SMN1; SMN2 | |
| SCHEMBL11315150 | 0.85 | AKR1C3 (0.51) | CYP2D6ACHEALOX5ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10918260 | 0.83 | AKR1C3 (0.50) | CYP2D6ACHEALOX5ALDH1A1SMN1; SMN2 | |
| SCHEMBL15554269 | 0.83 | CYP2D6 (0.70) | CYP2D6ALOX5ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3392489 | 0.83 | CYP2D6 (0.70) | CYP2D6ALOX5ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27383313 | 0.81 | KEAP1 (0.49) | ACHEALOX5ALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL11436603 | 0.81 | CYP2D6 (0.74) | CYP2D6SMN1; SMN2KEAP1NFE2L2LMNA | |
| SCHEMBL6393928 | 0.79 | CYP2D6 (0.57) | CYP2D6ALDH1A1LMNAPTGS2 | |
| SCHEMBL9862669 | 0.79 | AKR1C3 (0.58) | ALOX5ALDH1A1AKR1C3AKR1C2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028422-B1 | PROCESS FOR PREPARING ALCOHOLS FROM CARBOXYLIC ACIDS AND PROCESS FOR PREPARING CARBOXYLIC ACIDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4317918-A | Process for preparing alcohols | SUMITOMO CHEMICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |
| EP-0028422-A1 | Process for preparing alcohols from carboxylic acids and process for preparing carboxylic acids | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-13 | — | — | EP | disclosed |