Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.60 |
| ▸ | RECQL | P46063 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | TLR3 | O15455 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160990 | 0.83 | KIT (0.69) | KITRECQLKDM4EMEN1NR3C1 | |
| SCHEMBL31362095 | 0.83 | KIT (0.69) | KITRECQLKDM4EMEN1NR3C1 | |
| SCHEMBL11218842 | 0.83 | KIT (0.56) | KITRECQLKDM4EMEN1NR3C1 | |
| SCHEMBL5309123 | 0.80 | KDM4E (0.76) | KITRECQLKDM4EMEN1NR3C1 | |
| SCHEMBL11866502 | 0.78 | KIT (0.70) | KITRECQLKDM4EMEN1NR3C1 | |
| SCHEMBL26836186 | 0.78 | KIT (0.73) | KITRECQLKDM4EMEN1NR3C1 | |
| SCHEMBL1005968 | 0.76 | KIT (1.00) | KITRECQLKDM4EMEN1NR3C1 | |
| SCHEMBL5294321 | 0.75 | KIT (0.69) | KITRECQLKDM4EMEN1NR3C1 | |
| SCHEMBL11831488 | 0.75 | KIT (0.74) | KITRECQLKDM4EMEN1NR3C1 | |
| SCHEMBL9439101 | 0.74 | KIT (0.64) | KITRECQLKDM4EMEN1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009445-B1 | PROCESS FOR THE PREPARATION OF 9-HYDROXY-ELLIPTICINE AND DERIVATIVES THEREOF | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1983-05-18 | — | — | EP | claimed |