Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | TLR3 | O15455 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.61 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160990 | 1.00 | KIT (0.69) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL5309123 | 0.85 | KDM4E (0.76) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL26836186 | 0.84 | KIT (0.73) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL11210322 | 0.83 | KIT (0.60) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL1005968 | 0.82 | KIT (1.00) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL11866502 | 0.82 | KIT (0.70) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL8821070 | 0.82 | KIT (0.56) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL5294321 | 0.81 | KIT (0.69) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL9439101 | 0.80 | KIT (0.64) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL8821071 | 0.79 | KMT2A (0.66) | KITMAPTKDM4EMEN1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551095-B | Ellipticine derivative and preparation method and application thereof | 中国药科大学 | 2025-02-07 | — | — | CN | disclosed |