Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20917468 | 0.82 | KDM4E (0.51) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL30165796 | 0.82 | KDM4E (0.51) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7910817 | 0.82 | SLC16A3 (0.56) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL4495071 | 0.81 | KDM4E (0.49) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL25997345 | 0.81 | AGPAT2 (0.53) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL29462441 | 0.80 | KDM4E (0.74) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7123865 | 0.79 | NPC1 (0.60) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7120318 | 0.79 | NPC1 (0.75) | NPC1RAB9AMAOBCA1CA2 | |
| SCHEMBL20786805 | 0.79 | KDM4E (0.46) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2389126 | 0.79 | MAPT (0.64) | MAPTNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021304-B1 | COUMARIN COMPOUNDS, THEIR PREPARATION AND THEIR USE AS DYESTUFFS | BAYER AG (DE) | 1983-02-16 | — | — | EP | disclosed |
| EP-0021304-A1 | Coumarin compounds, their preparation and their use as dyestuffs | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |