Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20917468 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22371428 | 0.83 | KDM4E (0.74) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29462441 | 0.83 | KDM4E (0.74) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22371457 | 0.82 | MAPT (0.53) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL25997345 | 0.82 | AGPAT2 (0.53) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11210328 | 0.82 | MAPT (0.63) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4495071 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2389126 | 0.82 | MAPT (0.64) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31388377 | 0.82 | MAPT (0.64) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20786805 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654681-B | Exocyclic amine substituted coumarin compound and application thereof as fluorescent marker | 伊卢米纳剑桥有限公司 | 2023-01-06 | — | — | CN | disclosed |