Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17633755 | 0.98 | HRH1 (0.63) | HRH1CYP1A2CYP2D6CYP2C19HTT | |
| Hydrochloric Acid SCHEMBL31146770 | 0.98 | HRH1 (0.63) | HRH1CYP1A2CYP2D6CYP2C19HTT | |
| Hydrochloric Acid SCHEMBL11207809 | 0.98 | HRH1 (0.63) | HRH1CYP1A2CYP2D6CYP2C19HTT | |
| Hydrochloric Acid SCHEMBL31146769 | 0.98 | HRH1 (0.63) | HRH1CYP1A2CYP2D6CYP2C19HTT | |
| SCHEMBL1825837 | 0.88 | HTT (0.58) | HRH1HTTMAPK1TP53ALDH1A1 | |
| SCHEMBL29595035 | 0.88 | HTT (0.58) | HRH1HTTMAPK1TP53ALDH1A1 | |
| SCHEMBL31058801 | 0.85 | HTT (0.55) | HRH1HTTMAPK1TP53ALDH1A1 | |
| SCHEMBL31058797 | 0.85 | HTT (0.55) | HRH1HTTMAPK1TP53ALDH1A1 | |
| SCHEMBL21427814 | 0.85 | HTT (0.55) | HRH1HTTMAPK1TP53ALDH1A1 | |
| SCHEMBL31058794 | 0.85 | HTT (0.55) | HRH1HTTMAPK1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488544-B1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | UNIV MONASH (AU) | 2015-03-18 | — | — | EP | disclosed |
| US-8748582-B2 | Affinity ligands and methods for protein purification | MONASH UNIVERSITY (AU) | 2014-06-10 | — | — | US | disclosed |
| US-8748582-B2 | Affinity ligands and methods for protein purification | MONASH UNIVERSITY (AU) | 2014-06-10 | — | — | US | disclosed |
| US-20120259094-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MONASH UNIVERSITY | 2012-10-11 | — | — | US | disclosed |
| US-20120259094-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MONASH UNIVERSITY | 2012-10-11 | — | — | US | disclosed |
| WO-2011044637-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MONASH UNIVERSITY (AU) | 2011-04-21 | — | — | WO | disclosed |
| EP-0002930-B1 | AMINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1983-12-14 | — | — | EP | disclosed |
| US-4304780-A | Aminoalkylthiophene derivatives as histamine H2 -antagonists | GLAXO GROUP LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |
| US-4279911-A | ANTIHISTAMINES | GLAXO GROUP LIMITED (GB) | 1981-07-21 | — | — | US | disclosed |
| US-4233302-A | ANTIHISTAMINES, ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1980-11-11 | — | — | US | disclosed |
| EP-0002930-A1 | Amine derivatives, their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1979-07-11 | — | — | EP | disclosed |
| US-4080459-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-03-21 | — | — | US | disclosed |
| US-4067984-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-01-10 | — | — | US | disclosed |
| US-4013769-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120259094-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MAX, SPR, CCL2 | HRH1 1554/4885CYP1A2 3926/4885CYP2D6 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.