SCHEMBL11210355

SCHEMBL11210355

CCCCc1ccc(CCCCS)cc1CCCCS

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.43
TLR8 Q9NR97 6/20 0.41
TYR P14679 1/20 0.41
GPR3 P46089 1/20 0.40
ESR1 P03372 2/20 0.39
ADRA2A P08913 2/20 0.39
ADORA3 P0DMS8 2/20 0.39
TACR2 P21452 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
MAPK1 P28482 2/20 0.39
HTT P42858 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
SHBG P04278 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
HSPD1 P10809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9485320 0.89 SKP2 (0.52) SKP2TYRGPR3ESR1ADRA2A
SCHEMBL28004760 0.87 SKP2 (0.50) SKP2TYRGPR3ESR1ADRA2A
SCHEMBL8561136 0.87 CYP3A4 (0.50) TLR8TYRGPR3ESR1ADRA2A
SCHEMBL9862310 0.85 PTGS2 (0.53) TLR8TYRGPR3ESR1ADRA2A
SCHEMBL9862240 0.85 PTGS2 (0.53) TLR8TYRGPR3ESR1ADRA2A
SCHEMBL18242314 0.84 SKP2 (0.44) SKP2TLR8TYRMAPK1HTT
Ethylene SCHEMBL28058316 0.83 CYP3A4 (0.47) TLR8TYRGPR3ESR1ADRA2A
SCHEMBL18243587 0.82 SKP2 (0.43) SKP2TYRGPR3ESR1ADRA2A
SCHEMBL31003493 0.82 ESR1 (0.47) TLR8TYRGPR3ESR1ADRA2A
Ethylene SCHEMBL28058323 0.81 ESR1 (0.50) TLR8TYRGPR3ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108431149-B Anti-biofouling coatings based on epoxy resins and amine functional polysiloxanes 陶氏环球技术有限责任公司 2020-11-20 CN disclosed
EP-0014745-B1 CURING AGENT FOR POLYEPOXIDES, CURABLE EPOXY RESIN COMPOSITIONS, HARDENED PRODUCTS THEREFROM AND PROCESS FOR CURING A POLYEPOXIDE DIAMOND SHAMROCK CORPORATION (US) 1983-05-25 EP disclosed
EP-0075827-A2 Polyepoxide curing by polymercaptans plus catalytic co-curing agents DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1983-04-06 EP disclosed
EP-0014745-A1 Curing agent for polyepoxides, curable epoxy resin compositions, hardened products therefrom and process for curing a polyepoxide DIAMOND SHAMROCK CORPORATION (US) 1980-09-03 EP disclosed
US-4177173-A INFUSIBLE FILMS, CASTINGS OR ADHESIVES DIAMOND SHAMROCK CORPORATION (US) 1979-12-04 US disclosed