Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | BRD1 | O95696 | 1/20 | 0.33 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197021 | 0.80 | AR (0.40) | TRPV4ARPLA2G4ALTB4RSLC6A4 | |
| SCHEMBL1855982 | 0.77 | AR (0.49) | TRPV4ARUSP2MAPTPLA2G4A | |
| SCHEMBL2725970 | 0.75 | AR (0.44) | TRPV4ARUSP2MAPTPLA2G4A | |
| SCHEMBL7667004 | 0.73 | AR (0.47) | TRPV4ARUSP2MAPTPLA2G4A | |
| SCHEMBL6119537 | 0.72 | ALDH1A1 (0.41) | TRPV4ARUSP2MAPTPLA2G4A | |
| SCHEMBL2724187 | 0.71 | KCNH2 (0.45) | ARPLA2G4ALTB4RSLC6A4 | |
| SCHEMBL13098166 | 0.71 | AR (0.43) | TRPV4ARSLC6A4 | |
| SCHEMBL21170173 | 0.70 | AR (0.40) | ARPLA2G4ALTB4RSLC6A4PTGES2 | |
| SCHEMBL10944609 | 0.70 | AR (0.49) | TRPV4ARUSP2MAPTSLC6A4 | |
| SCHEMBL22481567 | 0.70 | AR (0.47) | TRPV4ARMAPTSLC6A4PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068590-A1 | Novel urea derivatives | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |