Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 8/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11444447 | 0.89 | ABCB1 (0.39) | ABCB1ABCC9KDM4EKCNE1KCNQ1 | |
| SCHEMBL11451772 | 0.87 | KCNE1 (0.38) | ABCB1ABCC9KDM4EKCNE1KCNQ1 | |
| SCHEMBL11444446 | 0.86 | KDM4E (0.42) | ABCB1ABCC9KDM4ECYP3A4CYP1A2 | |
| SCHEMBL11443884 | 0.86 | ABCB1 (0.38) | ABCB1KDM4E | |
| SCHEMBL11453216 | 0.85 | KCNE1 (0.38) | ABCB1ABCC9KDM4EKCNE1KCNQ1 | |
| SCHEMBL11453213 | 0.82 | KDM4E (0.39) | ABCB1ABCC9KDM4ECYP3A4ALOX15 | |
| SCHEMBL11461367 | 0.82 | ABCB1 (0.40) | ABCB1ABCC9 | |
| SCHEMBL11461364 | 0.81 | KDM4E (0.36) | ABCB1ABCC9KDM4ECYP1A2CYP2D6 | |
| SCHEMBL11444000 | 0.78 | ABCB1 (0.38) | ABCB1ABCC9KDM4ECYP1A2CYP2D6 | |
| SCHEMBL11443852 | 0.77 | CXCR1 (0.40) | ABCB1ABCC9KDM4ECYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | claimed |
| US-4333759-A | Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones | FISONS LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |