Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CTSA | P10619 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503892 | 0.87 | TSHR (0.51) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL10913569 | 0.84 | TSHR (0.49) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL10923063 | 0.84 | TSHR (0.49) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL27864282 | 0.84 | TSHR (0.52) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL8007070 | 0.84 | TSHR (0.49) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL10863285 | 0.82 | TSHR (0.57) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL11204062 | 0.81 | TSHR (0.46) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL4650563 | 0.79 | MAPT (0.53) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL10924082 | 0.79 | TSHR (0.47) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL18686284 | 0.77 | MAPT (0.56) | TSHRMAPTALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038987-B1 | PROCESS FOR PREPARING ACYL CYANIDES | BAYER AG (DE) | 1983-06-08 | — | — | EP | disclosed |
| EP-0038987-A1 | Process for preparing acyl cyanides | BAYER AG (DE) | 1981-11-04 | — | — | EP | disclosed |