Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19322442 | 0.84 | MAPT (0.71) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL19322447 | 0.83 | ALKBH5 (0.54) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL10863285 | 0.81 | TSHR (0.57) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL27864282 | 0.80 | TSHR (0.52) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL9503892 | 0.79 | TSHR (0.51) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL4348322 | 0.78 | ALKBH5 (0.57) | MAPTALDH1A1LMNAPOLBGAA | |
| SCHEMBL10913569 | 0.77 | TSHR (0.49) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL8007070 | 0.77 | TSHR (0.49) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL10923063 | 0.77 | TSHR (0.49) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL11211058 | 0.77 | TSHR (0.49) | MAPTALDH1A1LMNAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1862198-B1 | Brightening and/or dyeing agent with urea derivatives | HENKEL AG & CO KGAA (DE) | 2017-04-05 | — | — | EP | claimed |