Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211401 | 1.00 | LSS (0.39) | LSSHPGDHTTKMT2AATM | |
| SCHEMBL3277907 | 0.96 | HPGD (0.38) | LSSHPGDHTTKMT2AATM | |
| SCHEMBL10801575 | 0.93 | CYP2C9 (0.39) | LSSHPGDATMCNR1CNR2 | |
| SCHEMBL8377095 | 0.90 | CHRNA3 (0.42) | HPGDHTTKMT2AATMMEN1 | |
| SCHEMBL8377094 | 0.90 | CHRNA3 (0.42) | HPGDHTTKMT2AATMMEN1 | |
| SCHEMBL8455675 | 0.89 | TDP1 (0.42) | HTTKMT2AATMMEN1CA2 | |
| SCHEMBL7508867 | 0.89 | TDP1 (0.42) | HTTKMT2AATMMEN1CA2 | |
| SCHEMBL20152463 | 0.89 | TDP1 (0.42) | HTTKMT2AATMMEN1CA2 | |
| SCHEMBL3285878 | 0.88 | HPGD (0.40) | HPGDHTTKMT2AATMMEN1 | |
| SCHEMBL11034715 | 0.88 | HPGD (0.40) | HPGDHTTKMT2AATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58013544-A | — | — | None | — | — | JP | disclosed |
| JP-S5813544-A | TRANS-4-SUBSTITUTED CYCLOHEXANECARBOXYLIC ACID 3-CHLORO-4- FLUOROPHENYL ESTER | CHISSO CORP | 1983-01-26 | — | — | JP | disclosed |