Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.45 |
| ▸ | ACE | P12821 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185141 | 0.88 | GAA (0.66) | GAAPOLBRAB9ATSHRSMN1; SMN2 | |
| SCHEMBL11107571 | 0.87 | POLB (0.49) | GAAPOLBRAB9AACE | |
| SCHEMBL11100929 | 0.87 | HSD17B10 (0.52) | GAAPOLBRAB9AFFAR2ACE | |
| SCHEMBL11200469 | 0.86 | POLB (0.48) | GAAPOLBRAB9AACE | |
| SCHEMBL11244020 | 0.86 | POLB (0.48) | GAAPOLBRAB9AACE | |
| SCHEMBL11258909 | 0.84 | POLB (0.46) | GAAPOLBRAB9AACE | |
| SCHEMBL11107129 | 0.84 | POLB (0.46) | GAAPOLBRAB9AACE | |
| SCHEMBL11109577 | 0.84 | GAA (0.47) | GAAPOLBRAB9ATSHRFFAR2 | |
| SCHEMBL11100835 | 0.83 | POLB (0.47) | GAAPOLBRAB9AACE | |
| SCHEMBL11257128 | 0.82 | GAA (0.58) | GAAPOLBRAB9ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410542-A | HYPOTENSIVE AGENTS, PYRROLINE-1,2-DICARBOXYLIC ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |