Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200469 | 1.00 | POLB (0.48) | POLBGAARAB9AACE | |
| SCHEMBL11100929 | 0.89 | HSD17B10 (0.52) | POLBGAARAB9AACE | |
| SCHEMBL11184570 | 0.87 | POLB (0.47) | POLBGAARAB9A | |
| SCHEMBL11107571 | 0.87 | POLB (0.49) | POLBGAARAB9AACE | |
| SCHEMBL11247271 | 0.87 | KDM4E (0.45) | ACE | |
| SCHEMBL11189829 | 0.87 | KDM4E (0.45) | ACE | |
| SCHEMBL11211523 | 0.86 | GAA (0.67) | POLBGAARAB9AACE | |
| SCHEMBL11474215 | 0.84 | POLB (0.47) | POLBGAARAB9AACE | |
| SCHEMBL11474211 | 0.84 | POLB (0.47) | POLBGAARAB9AACE | |
| SCHEMBL11474221 | 0.84 | POLB (0.47) | POLBGAARAB9AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356183-A | ENZYME INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-10-26 | — | — | US | claimed |