SCHEMBL11211537

SCHEMBL11211537

Cc1cc(N)sc1[N+](=O)[O-]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.42
CYP3A4 P08684 4/20 0.42
TDP1 Q9NUW8 4/20 0.42
TSHR P16473 6/20 0.41
RECQL P46063 1/20 0.41
GAA P10253 1/20 0.40
HPGD P15428 3/20 0.34
HTT P42858 3/20 0.34
ALOX15 P16050 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 2/20 0.33
CCR6 P51684 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A2 P05177 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PKM P14618 1/20 0.33
NLRP1 Q9C000 1/20 0.33
GALR2 O43603 1/20 0.33
MPI P34949 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12391229 0.78 ALDH1A1 (0.39) ALDH1A1CYP3A4TDP1TSHRRECQL
SCHEMBL8257200 0.75 ALDH1A1 (0.41) ALDH1A1CYP3A4TDP1TSHRGAA
SCHEMBL30487441 0.75 CYP1A2 (0.41) ALDH1A1CYP3A4TDP1TSHRRECQL
SCHEMBL12207825 0.72 HTT (0.35) ALDH1A1CYP3A4TDP1TSHRRECQL
SCHEMBL12446507 0.72 HTT (0.36) ALDH1A1CYP3A4TDP1TSHRRECQL
SCHEMBL12202920 0.71 ALDH1A1 (0.46) ALDH1A1CYP3A4TDP1TSHRRECQL
SCHEMBL29016889 0.71 DAO (0.55) ALDH1A1TDP1TSHRALOX15POLB
SCHEMBL12597663 0.71 ALDH1A1 (0.33) ALDH1A1CYP3A4TDP1TSHRRECQL
SCHEMBL782281 0.70 ALDH1A1 (0.50) ALDH1A1CYP3A4TDP1TSHRGAA
SCHEMBL18357510 0.68 ALDH1A1 (0.44) ALDH1A1CYP3A4TDP1TSHRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4313872-A MONDAZO AND DISAZO DYES CASSELLA AKTIENGESELLSCHAFT (DE) 1982-02-02 US disclosed