SCHEMBL11211705

SCHEMBL11211705

CCCC(CCC)(C(=O)O)C(=O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
TSHR P16473 1/20 0.35
FFAR3 O14843 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
FDPS P14324 2/20 0.31
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2599668 0.91 ALDH1A1 (0.33) ALDH1A1TSHRMEN1CYP1A2THRB
SCHEMBL1031267 0.84 FFAR3 (0.38) ALDH1A1TSHRFFAR3HDAC3HDAC1
SCHEMBL21269721 0.81 FFAR3 (0.36) ALDH1A1TSHRFFAR3HDAC3HDAC1
SCHEMBL28314587 0.81 FFAR3 (0.36) ALDH1A1TSHRFFAR3HDAC3HDAC1
SCHEMBL21269954 0.81 FFAR3 (0.36) ALDH1A1TSHRFFAR3HDAC3HDAC1
Hydrochloric Acid SCHEMBL809273 0.81 FFAR3 (0.36) ALDH1A1TSHRFFAR3HDAC3HDAC1
SCHEMBL21269884 0.81 FFAR3 (0.36) ALDH1A1TSHRFFAR3HDAC3HDAC1
SCHEMBL1033008 0.79 ALDH1A1 (0.38) ALDH1A1TSHRFFAR3HDAC3HDAC1
SCHEMBL3062956 0.79 ALDH1A1 (0.38) ALDH1A1TSHRFFAR3MEN1CYP1A2
SCHEMBL16054795 0.77 ALDH1A1 (0.37) ALDH1A1TSHRFFAR3HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0029719-B1 VULCANIZABLE RUBBER COMPOSITIONS INHIBITED FROM PREMATURE VULCANIZATION BY METHYLENE THIOETHERS, AND NOVEL METHYLENE THIOETHERS MONSANTO COMPANY (US) 1983-02-16 EP disclosed
US-4342705-A CONTAINING CARBONYL OR CYANO FUNCTIONAL GROUPS, USEFUL AS VULCANIZATION INHIBITORS MONSANTO COMPANY (US) 1982-08-03 US disclosed
EP-0029719-A1 Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers, and novel methylene thioethers MONSANTO COMPANY (US) 1981-06-03 EP disclosed
US-4271050-A Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers MONSANTO COMPANY (US) 1981-06-02 US disclosed