Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212591 | 1.00 | MGLL (0.47) | MGLLPOLBGRM2RXFP1PGR | |
| SCHEMBL11209166 | 1.00 | MGLL (0.47) | MGLLPOLBGRM2RXFP1PGR | |
| SCHEMBL11208072 | 1.00 | MGLL (0.47) | MGLLPOLBGRM2RXFP1PGR | |
| SCHEMBL11212590 | 1.00 | MGLL (0.47) | MGLLPOLBGRM2RXFP1PGR | |
| SCHEMBL11208069 | 1.00 | MGLL (0.47) | MGLLPOLBGRM2RXFP1PGR | |
| SCHEMBL11073582 | 0.99 | MGLL (0.46) | MGLLPOLBGRM2RXFP1PGR | |
| SCHEMBL11073584 | 0.99 | MGLL (0.46) | MGLLPOLBGRM2RXFP1PGR | |
| SCHEMBL11211535 | 0.96 | MGLL (0.46) | MGLLPOLBRXFP1PGRUBE2N | |
| SCHEMBL11211533 | 0.96 | MGLL (0.46) | MGLLPOLBRXFP1PGRUBE2N | |
| SCHEMBL5687273 | 0.95 | MGLL (0.45) | MGLLPOLBGRM2RXFP1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391731-A | Hydrogenated naphthalenes | HOFFMANN-LA ROCHE INC. (US) | 1983-07-05 | — | — | US | disclosed |