Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.57 |
| ▸ | FEN1 | P39748 | 8/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31721266 | 0.85 | NUDT1 (0.49) | NUDT1FEN1ALOX5APHSP90AA1HRH4 | |
| SCHEMBL12813082 | 0.83 | POLB (0.54) | NUDT1FEN1ALOX5APHSP90AA1AURKA | |
| SCHEMBL1892428 | 0.83 | MEN1 (0.50) | NUDT1FEN1ALOX5APKCNH2SCN9A | |
| SCHEMBL18629754 | 0.82 | FEN1 (0.50) | NUDT1FEN1ALOX5APGRM4KDM4E | |
| SCHEMBL30790323 | 0.81 | — | — | |
| SCHEMBL3121960 | 0.81 | — | — | |
| SCHEMBL359919 | 0.81 | — | — | |
| SCHEMBL31403749 | 0.80 | MAP4K4 (0.51) | NUDT1ROCK1ALDH1A1 | |
| SCHEMBL30048005 | 0.80 | POLB (0.51) | NUDT1FEN1ALOX5APHSP90AA1AURKA | |
| SCHEMBL28189689 | 0.79 | NUDT1 (0.61) | NUDT1FEN1ALOX5APHSP90AA1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055692-A1 | Novel pyrimidinyl ethers, their use as herbicides, herbicidal compositions comprising said pyrimidinyl ethers and processes for the preparation thereof | SANDOZ AG (CH) | 1982-07-07 | — | — | EP | claimed |
| US-4400201-A | 2-AMINO-4-CYCLOPROPYLMETHOXY-SUBSTITUTED | SANDOZ LTD. (CH) | 1983-08-23 | — | — | US | disclosed |
| EP-0055692-A1 | Novel pyrimidinyl ethers, their use as herbicides, herbicidal compositions comprising said pyrimidinyl ethers and processes for the preparation thereof | SANDOZ AG (CH) | 1982-07-07 | — | — | EP | disclosed |