Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212393 | 1.00 | TP53 (0.47) | TP53HTTMEN1KMT2APKM | |
| SCHEMBL6459239 | 0.98 | TP53 (0.45) | TP53HTTMEN1KMT2APKM | |
| SCHEMBL6459237 | 0.98 | TP53 (0.45) | TP53HTTMEN1KMT2APKM | |
| SCHEMBL11208791 | 0.94 | POLB (0.43) | TP53HTTMEN1KMT2APKM | |
| SCHEMBL11208792 | 0.94 | POLB (0.43) | TP53HTTMEN1KMT2APKM | |
| SCHEMBL17065550 | 0.90 | TP53 (0.51) | TP53HTTMEN1KMT2APKM | |
| SCHEMBL5599221 | 0.87 | LMNA (0.41) | TP53MEN1KMT2APKMCYP2C9 | |
| SCHEMBL6459367 | 0.87 | LMNA (0.41) | TP53MEN1KMT2APKMCYP2C9 | |
| SCHEMBL5599223 | 0.87 | LMNA (0.41) | TP53MEN1KMT2APKMCYP2C9 | |
| SCHEMBL10828238 | 0.86 | HTT (0.43) | TP53HTTMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391731-A | Hydrogenated naphthalenes | HOFFMANN-LA ROCHE INC. (US) | 1983-07-05 | — | — | US | disclosed |