Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609047 | 0.81 | TSHR (0.45) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL863124 | 0.80 | TSHR (0.43) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL8970195 | 0.79 | TSHR (0.39) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL3020917 | 0.78 | TSHR (0.42) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL11207253 | 0.78 | — | — | |
| SCHEMBL8979235 | 0.78 | — | — | |
| SCHEMBL129854 | 0.78 | — | — | |
| SCHEMBL11207275 | 0.76 | — | — | |
| SCHEMBL9764293 | 0.76 | TSHR (0.41) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL12799562 | 0.76 | TSHR (0.41) | TSHRCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4398913-A | ALKALINE PASTES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |