Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120873 | 0.90 | CYP1A2 (0.43) | GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL750971 | 0.83 | ALOX15 (0.43) | GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL25367647 | 0.78 | CYP1A2 (0.47) | GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL26114592 | 0.69 | GRM2 (0.32) | GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL1442126 | 0.66 | CYP1A2 (0.50) | GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL22468318 | 0.66 | CYP1A2 (0.50) | GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL22636233 | 0.66 | CYP1A2 (0.50) | GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL11212501 | 0.66 | CYP1A2 (0.46) | GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL24113083 | 0.66 | CYP1A2 (0.46) | GRM2GRM3CYP1A2ALOX15 | |
| SCHEMBL27113627 | 0.66 | BACE1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311697-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-01-19 | — | — | US | disclosed |