Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212874 | 1.00 | TSHR (0.32) | TSHRMEN1HPGDKMT2AACE | |
| SCHEMBL11213004 | 0.82 | ACE (0.31) | ACE | |
| SCHEMBL11213006 | 0.82 | ACE (0.31) | ACE | |
| SCHEMBL11215539 | 0.79 | ACE (0.32) | ACE | |
| SCHEMBL11212105 | 0.77 | ACE (0.42) | KMT2AACE | |
| SCHEMBL11210147 | 0.76 | ACE (0.50) | KMT2AACE | |
| SCHEMBL11214777 | 0.76 | ACE (0.50) | KMT2AACE | |
| SCHEMBL11212494 | 0.76 | ACE (0.31) | ACE | |
| SCHEMBL11212082 | 0.75 | ACE (0.36) | ACE | |
| SCHEMBL11212958 | 0.74 | ACE (0.38) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311697-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-01-19 | — | — | US | disclosed |