SCHEMBL11212871

SCHEMBL11212871

CC(C)C1OCC(Cn2cncn2)(c2ccc(Cl)cc2)O1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.43
CYP2C9 P11712 3/20 0.43
THRB P10828 1/20 0.42
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 2/20 0.41
HSP90AA1 P07900 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
KDM4E B2RXH2 2/20 0.36
POLB P06746 1/20 0.36
HTT P42858 1/20 0.36
NR1I2 O75469 1/20 0.35
LMNA P02545 1/20 0.35
FYN P06241 1/20 0.35
PGR P06401 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27545135 0.91 CYP3A4 (0.44) CYP3A4CYP2C9THRBCYP1A2CYP2D6
SCHEMBL9195741 0.82 CYP3A4 (0.47) CYP3A4CYP2C9THRBCYP1A2CYP2D6
SCHEMBL9567574 0.81 CYP3A4 (0.52) CYP3A4CYP2C9THRBCYP1A2CYP2D6
SCHEMBL10517012 0.81 CYP3A4 (0.46) CYP3A4CYP2C9THRBCYP1A2CYP2D6
SCHEMBL9665341 0.81 CYP3A4 (0.46) CYP3A4CYP2C9THRBCYP1A2CYP2D6
SCHEMBL27545132 0.79 CYP3A4 (0.44) CYP3A4CYP2C9THRBCYP1A2CYP2D6
SCHEMBL10594681 0.76 CYP3A4 (0.48) CYP3A4CYP2C9THRBCYP1A2CYP2D6
SCHEMBL10594041 0.76 CYP3A4 (0.46) CYP3A4CYP2C9THRBCYP1A2CYP2D6
SCHEMBL9201220 0.75 CYP3A4 (0.49) CYP3A4CYP2C9THRBCYP1A2CYP2D6
SCHEMBL10594716 0.74 CYP3A4 (0.54) CYP3A4CYP2C9THRBCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0094167-A2 Azolyl fungicide and plant growth regulators and compositions containing them FBC LIMITED (GB) 1983-11-16 EP disclosed