Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213133 | 1.00 | ACHE (0.43) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL2893103 | 0.88 | ACHE (0.53) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL2893106 | 0.88 | ACHE (0.53) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL4314107 | 0.82 | — | — | |
| SCHEMBL263011 | 0.82 | — | — | |
| SCHEMBL11366686 | 0.78 | HCAR2 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL11366710 | 0.78 | HCAR2 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL10970806 | 0.77 | ACHE (0.46) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL1259562 | 0.77 | ACHE (0.46) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL11356547 | 0.76 | HCAR2 (0.47) | HCAR2TSHRCYP3A4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034120-B1 | DERIVATIVES OF PHENOXY-PHENOXY-CARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1983-12-14 | — | — | EP | disclosed |
| US-4254262-A | IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |