Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.68 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848088 | 0.81 | PDE3B (1.00) | PDE3BPDE3APSMB8HSD17B10MAPT | |
| SCHEMBL1856589 | 0.81 | PDE3B (0.59) | PDE3BPDE3APSMB8HSD17B10MAPT | |
| SCHEMBL28132827 | 0.80 | PSMB8 (1.00) | PDE3BPDE3APSMB8HSD17B10MAPT | |
| SCHEMBL28195083 | 0.75 | PDE3B (0.65) | PDE3BPDE3APSMB8MAPTALDH1A1 | |
| SCHEMBL1286050 | 0.74 | PSMB8 (0.41) | PDE3BPDE3APSMB8HSD17B10MAPT | |
| SCHEMBL9204486 | 0.74 | MAPT (0.59) | PDE3BPDE3AMAPTALDH1A1PKM | |
| SCHEMBL3232045 | 0.74 | HSD17B10 (0.80) | PDE3BPDE3APSMB8HSD17B10MAPT | |
| SCHEMBL21676421 | 0.74 | HSD17B10 (1.00) | PDE3BPDE3APSMB8HSD17B10MAPT | |
| SCHEMBL11104196 | 0.73 | PDE3B (0.63) | PDE3BPDE3AMAPTKMT2AHTT | |
| SCHEMBL7767367 | 0.73 | HCRTR1 (0.65) | PDE3BPDE3AHSD17B10MAPTESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022213-A1 | Medicaments containing benzothiazole-2(3H)-one derivatives | Dr. Karl Thomae GmbH (DE) | 1981-01-14 | — | — | EP | claimed |
| CN-115246795-B | Isoxazoline compound containing ether structure at 4-phenyl para-position, preparation method thereof and application thereof as insecticidal and bactericidal agent | 瑞普（天津）生物药业有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-115246795-A | Isoxazoline compound with 4-phenyl para-position containing ether structure, preparation thereof and application thereof as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | disclosed |
| US-4328235-A | SUPPRESSION OF PAIN | BOEHRINGER INGELHEIM GMBH (DE) | 1982-05-04 | — | — | US | disclosed |
| EP-0022213-A1 | Medicaments containing benzothiazole-2(3H)-one derivatives | Dr. Karl Thomae GmbH (DE) | 1981-01-14 | — | — | EP | disclosed |