Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213289 | 1.00 | TLR4 (0.33) | TLR4PLGPLATLMNACHRNB2 | |
| SCHEMBL11209632 | 0.85 | PLG (0.44) | PLGPLATLMNA | |
| SCHEMBL11209634 | 0.85 | PLG (0.44) | PLGPLATLMNA | |
| SCHEMBL11209160 | 0.84 | ABL1 (0.37) | TLR4LMNA | |
| SCHEMBL11209157 | 0.84 | ABL1 (0.37) | TLR4LMNA | |
| SCHEMBL19250775 | 0.84 | CHRNB2 (0.34) | TLR4CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL11211012 | 0.83 | SMN1; SMN2 (0.39) | TLR4PLGPLATLMNA | |
| SCHEMBL11207021 | 0.83 | SMN1; SMN2 (0.39) | TLR4PLGPLATLMNA | |
| SCHEMBL11207022 | 0.83 | SMN1; SMN2 (0.39) | TLR4PLGPLATLMNA | |
| SCHEMBL11209622 | 0.82 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391731-A | Hydrogenated naphthalenes | HOFFMANN-LA ROCHE INC. (US) | 1983-07-05 | — | — | US | disclosed |