Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30304769 | 0.80 | TDP1 (0.50) | TDP1ALDH1A1POLBTXNRD1TXNRD3 | |
| SCHEMBL14352772 | 0.80 | TDP1 (0.50) | TDP1ALDH1A1POLBTXNRD1TXNRD3 | |
| SCHEMBL8392625 | 0.80 | TDP1 (0.50) | TDP1ALDH1A1POLBTXNRD1TXNRD3 | |
| SCHEMBL28966398 | 0.80 | TDP1 (0.50) | TDP1ALDH1A1POLBTXNRD1TXNRD3 | |
| SCHEMBL27349934 | 0.78 | TDP1 (0.47) | TDP1ALDH1A1POLBTXNRD1TXNRD3 | |
| SCHEMBL6770368 | 0.76 | TDP1 (0.46) | TDP1ALDH1A1POLBTXNRD1TXNRD3 | |
| SCHEMBL11747535 | 0.74 | CHUK (0.38) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL30999970 | 0.73 | TXNRD1 (0.42) | TDP1ALDH1A1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL11103185 | 0.73 | TDP1 (0.50) | TDP1ALDH1A1POLBTXNRD1TXNRD3 | |
| SCHEMBL17224000 | 0.73 | TDP1 (0.42) | TDP1ALDH1A1POLBTXNRD1TXNRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |
| US-3998802-A | POLYAMIDES, CELLULOSE ESTERS, POLYESTERS, POLYACRYLONITRILES | BASF AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |