Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SAT1 | P21673 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26052132 | 1.00 | CYP2C19 (0.55) | CYP2C19CYP1A2KDM1AMEN1KMT2A | |
| SCHEMBL15563084 | 1.00 | CYP2C19 (0.55) | CYP2C19CYP1A2KDM1AMEN1KMT2A | |
| SCHEMBL17780060 | 1.00 | CYP2C19 (0.55) | CYP2C19CYP1A2KDM1AMEN1KMT2A | |
| SCHEMBL11477230 | 1.00 | CYP2C19 (0.55) | CYP2C19CYP1A2KDM1AMEN1KMT2A | |
| SCHEMBL10712359 | 1.00 | CYP2C19 (0.55) | CYP2C19CYP1A2KDM1AMEN1KMT2A | |
| SCHEMBL10585603 | 1.00 | CYP2C19 (0.55) | CYP2C19CYP1A2KDM1AMEN1KMT2A | |
| SCHEMBL11205448 | 1.00 | CYP2C19 (0.55) | CYP2C19CYP1A2KDM1AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2112301 | 0.98 | CYP2C19 (0.52) | CYP2C19CYP1A2KDM1AMEN1KMT2A | |
| SCHEMBL441049 | 0.97 | CYP2C19 (0.57) | CYP2C19CYP1A2KDM1AMEN1KMT2A | |
| SCHEMBL20841975 | 0.91 | LMNA (0.58) | CYP2C19CYP1A2KDM1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105197-A1 | SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT | VINCERX PHARMA GMBH (DE) | 2024-05-23 | — | — | WO | disclosed |
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-11807636-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230234953-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230132715-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-05-04 | — | — | US | disclosed |
| EP-3199610-B1 | FUEL ADDITIVES AND FUELS CONTAINING THE ADDITIVES | AFTON CHEMICAL CORP (US) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020264490-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| EP-3199610-A1 | FUEL ADDITIVES AND FUELS CONTAINING THE ADDITIVES | Afton Chemical Corporation (US) | 2017-08-02 | — | — | EP | disclosed |
| US-9353326-B1 | Synergistic fuel additives and fuels containing the additives | AFTON CHEMICAL CORPORATION (US) | 2016-05-31 | — | — | US | disclosed |
| EP-0031924-B1 | USE OF ALCANOL-AMINE SALTS OF CYCLIC AMIDOCARBOXYLIC ACIDS AS CORROSION INHIBITORS IN AQUEOUS SYSTEMS | BASF Aktiengesellschaft (DE) | 1983-05-18 | — | — | EP | disclosed |
| EP-0031924-A1 | Use of alcanol-amine salts of cyclic amidocarboxylic acids as corrosion inhibitors in aqueous systems | BASF Aktiengesellschaft (DE) | 1981-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230132715-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | CYP2C19 3990/4885CYP1A2 3570/4885KDM1A 160/4885 |
| US-20230234953-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | CYP2C19 3990/4885CYP1A2 3570/4885KDM1A 160/4885 |
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | CYP2C19 3990/4885CYP1A2 3570/4885KDM1A 160/4885 |
| US-11807636-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | CYP2C19 3990/4885CYP1A2 3570/4885KDM1A 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.