Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.33 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465004 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL4882477 | 0.85 | — | — | |
| Methyl Carbamate SCHEMBL28244357 | 0.79 | BLM (0.42) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| Methyl Carbamate SCHEMBL29503962 | 0.79 | BLM (0.42) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL2891 | 0.73 | BLM (0.42) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL31648906 | 0.73 | BLM (0.42) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL27702892 | 0.73 | BLM (0.42) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| Methyl Carbamate SCHEMBL28068168 | 0.73 | CA14 (0.40) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL28257738 | 0.72 | BLM (0.36) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL601039 | 0.71 | KDM4E (0.52) | BLMKDM4ECYP2D6CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146569-B | Hyaluronic acid-artesunate-polyarginine nanoparticle, preparation method and application | 中国海洋大学 | 2024-11-22 | — | — | CN | claimed |
| CN-118146569-A | Hyaluronic acid-artesunate-polyarginine nanoparticle, preparation method and application | 中国海洋大学 | 2024-06-07 | — | — | CN | claimed |
| EP-0031109-B1 | GUANIDINIUM COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-05-11 | — | — | EP | claimed |
| CN-118146569-B | Hyaluronic acid-artesunate-polyarginine nanoparticle, preparation method and application | 中国海洋大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-118146569-A | Hyaluronic acid-artesunate-polyarginine nanoparticle, preparation method and application | 中国海洋大学 | 2024-06-07 | — | — | CN | disclosed |
| US-4339459-A | FUNGICIDES, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-13 | — | — | US | disclosed |