SCHEMBL11213720

SCHEMBL11213720

CC1CCC=CCCC=CCCC=CC(=O)C1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TLR4 O00206 1/20 0.33
HSP90AB1 P08238 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11213717 1.00 ALDH1A1 (0.37) ALDH1A1TLR4HSP90AB1
SCHEMBL11213716 1.00 ALDH1A1 (0.37) ALDH1A1TLR4HSP90AB1
SCHEMBL11205631 0.80 ALDH1A1 (0.43) ALDH1A1TLR4
SCHEMBL11205628 0.80 ALDH1A1 (0.43) ALDH1A1TLR4
SCHEMBL6080709 0.73
SCHEMBL5791644 0.73
SCHEMBL35514 0.68
SCHEMBL13799374 0.67 KMT2A (0.32)
SCHEMBL14716453 0.67 TRIM24 (0.36) ALDH1A1TLR4
SCHEMBL14418805 0.67 TRIM24 (0.36) ALDH1A1TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0015412-B1 UNSATURATED MACROCYCLIC KETONES; THEIR PREPARATION; PREPARATION OF SATURATED MACROCYCLIC KETONES; APPLICATION IN PERFUME AND FLAVOUR COMPOSITIONS OF SOME UNSATURATED MACROCYCLIC KETONES FIRMENICH SA (CH) 1983-05-18 EP claimed
US-4346023-A FLAVORS, PERFUMES FIRMENICH SA (CH) 1982-08-24 US claimed
EP-0015412-A2 Unsaturated macrocyclic ketones; their preparation; preparation of saturated macrocyclic ketones; application in perfume and flavour compositions of some unsaturated macrocyclic ketones FIRMENICH SA (CH) 1980-09-17 EP claimed