Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485022 | 0.86 | ALDH1A1 (0.52) | CYP2A6ALDH1A1HSD17B10CYP3A4HIF1A | |
| SCHEMBL1429141 | 0.83 | ALDH1A1 (0.50) | CYP2A6ALDH1A1HSD17B10CYP3A4HIF1A | |
| SCHEMBL31540581 | 0.78 | CYP2A6 (0.50) | CYP2A6ALDH1A1HSD17B10CYP3A4HIF1A | |
| SCHEMBL14742908 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP3A4HIF1AALOX15 | |
| SCHEMBL6754533 | 0.77 | CYP2A6 (0.48) | CYP2A6ALDH1A1HSD17B10CYP3A4HIF1A | |
| SCHEMBL24808798 | 0.76 | KDM4E (0.48) | CYP2A6ALDH1A1ALOX15HPRT1KDM4E | |
| SCHEMBL2763409 | 0.75 | NQO2 (0.47) | ALDH1A1HSD17B10CYP3A4HIF1AALOX15 | |
| SCHEMBL5749569 | 0.75 | CYP1A2 (0.47) | CYP2A6ALDH1A1HSD17B10CYP3A4HIF1A | |
| SCHEMBL4916323 | 0.74 | HPRT1 (0.57) | ALDH1A1HSD17B10CYP3A4HIF1AALOX15 | |
| SCHEMBL168479 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CYP3A4HIF1AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010842-B1 | POLYURETHANE FOAM AND METHOD OF PREPARATION THEREOF | UNIROYAL LTD. (CA) | 1983-09-21 | — | — | EP | disclosed |
| US-4209593-A | Semi-flexible shock-absorbing polyurethane foam prepared from a triol, a compound having a single reactive hydrogen, an aromatic polyisocyanate, blowing agent, chain-extender and a catalyst | UNIROYAL LTD. (CA) | 1980-06-24 | — | — | US | disclosed |
| EP-0010842-A1 | Polyurethane foam and method of preparation thereof | UNIROYAL LTD. (CA) | 1980-05-14 | — | — | EP | disclosed |