Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | OGT | O15294 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278834 | 0.86 | NOS1 (0.49) | NOS1PDE3BPDE3AOGTCREBBP | |
| SCHEMBL13080918 | 0.81 | NOS1 (0.46) | NOS1PDE3BPDE3AOGTCREBBP | |
| SCHEMBL9909873 | 0.77 | NOS1 (0.61) | NOS1PDE3BPDE3AOGTCREBBP | |
| SCHEMBL2547913 | 0.74 | NOS1 (0.57) | NOS1PDE3BPDE3AOGTCREBBP | |
| SCHEMBL18713322 | 0.73 | NOS1 (0.56) | NOS1PDE3BPDE3AOGTCREBBP | |
| Hydrochloric Acid SCHEMBL10538242 | 0.73 | NOS1 (0.47) | NOS1PDE3BPDE3AOGTCREBBP | |
| SCHEMBL18552760 | 0.72 | NOS1 (0.54) | NOS1PDE3BPDE3AOGTCREBBP | |
| SCHEMBL13969518 | 0.72 | NOS1 (0.54) | NOS1PDE3BPDE3AOGTCREBBP | |
| SCHEMBL3600957 | 0.71 | NOS1 (0.58) | NOS1PDE3BPDE3AOGTCREBBP | |
| SCHEMBL22382321 | 0.71 | NOS1 (0.49) | NOS1PDE3BPDE3AOGTCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1982001186-A1 | NOVEL BENZOXAZOLINONES,SUBSTITUTED IN THE 6-POSITION BY AN AMINOALCOHOL CHAIN OR AMINO-KETONE CHAIN,THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL PREPARATIONS | BUSCH N | 1982-04-15 | — | — | WO | disclosed |