Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495729 | 1.00 | CYP19A1 (0.50) | CYP19A1TSHRCYP3A4SMN1; SMN2HTT | |
| SCHEMBL7696997 | 1.00 | CYP19A1 (0.50) | CYP19A1TSHRCYP3A4SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL7787578 | 0.98 | CYP19A1 (0.48) | CYP19A1TSHRCYP3A4SMN1; SMN2HTT | |
| SCHEMBL30202589 | 0.91 | CYP19A1 (0.42) | CYP19A1TSHRCYP3A4SMN1; SMN2HTT | |
| SCHEMBL29250827 | 0.91 | CYP19A1 (0.42) | CYP19A1TSHRCYP3A4SMN1; SMN2HTT | |
| SCHEMBL29250829 | 0.91 | CYP19A1 (0.42) | CYP19A1TSHRCYP3A4SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL29723633 | 0.89 | CYP19A1 (0.41) | CYP19A1TSHRCYP3A4SMN1; SMN2HTT | |
| SCHEMBL25456950 | 0.88 | TSHR (0.61) | CYP19A1TSHRCYP3A4SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL29723280 | 0.87 | TSHR (0.59) | CYP19A1TSHRCYP3A4SMN1; SMN2HTT | |
| SCHEMBL6359586 | 0.84 | TSHR (0.57) | TSHRSMN1; SMN2HTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322310-A | Chiral supports for resolution of racemates | UOP INC. (US) | 1982-03-30 | — | — | US | disclosed |