SCHEMBL11214049

SCHEMBL11214049

Cc1cccc(S(=O)(=O)NNc2ccccc2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
HPGD P15428 4/20 0.68
ALOX12 P18054 3/20 0.68
CYP1A2 P05177 3/20 0.68
CYP3A4 P08684 3/20 0.68
CYP2C9 P11712 3/20 0.68
CYP2C19 P33261 3/20 0.68
KDM4E B2RXH2 3/20 0.68
TDP1 Q9NUW8 3/20 0.68
GFER P55789 2/20 0.68
CYP2D6 P10635 2/20 0.68
GAA P10253 2/20 0.68
IDO1 P14902 6/20 0.63
MAPT P10636 4/20 0.60
POLB P06746 1/20 0.60
APOBEC3G Q9HC16 2/20 0.56
KMT2A Q03164 3/20 0.56
PKM P14618 1/20 0.54
MEN1 O00255 2/20 0.53
KAT6A Q92794 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2665022 0.83 KMT2A (0.73) ALDH1A1HPGDKDM4EGAAMAPT
SCHEMBL7123611 0.82 IDO1 (0.75) ALDH1A1HPGDALOX12CYP1A2CYP3A4
SCHEMBL11161395 0.81 ALDH1A1 (1.00) ALDH1A1HPGDALOX12CYP1A2CYP3A4
SCHEMBL30642945 0.79 KMT2A (0.62) ALDH1A1HPGDKDM4EMAPTKMT2A
SCHEMBL15045213 0.77 KMT2A (0.71) ALDH1A1HPGDGAAMAPTKMT2A
SCHEMBL6920158 0.76 KMT2A (0.69) ALDH1A1HPGDKDM4EMAPTKMT2A
SCHEMBL31681311 0.76 CA12 (0.66) ALDH1A1HPGDGAAMAPTKMT2A
SCHEMBL259382 0.76 CA12 (0.66) ALDH1A1HPGDGAAMAPTKMT2A
SCHEMBL29007531 0.75 HPGD (0.87) ALDH1A1HPGDALOX12CYP1A2CYP3A4
SCHEMBL22635619 0.75 IDO1 (0.56) ALDH1A1HPGDALOX12CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0019198-B1 PROCESS FOR PREPARING POLYMERS OF VINYL CHLORIDE, COMPOSITION FOR COATING POLYMERIZATION VESSELS AND POLYMERIZATION VESSEL COATED THEREWITH HOECHST AKTIENGESELLSCHAFT (DE) 1983-11-23 EP disclosed
EP-0019198-A1 Process for preparing polymers of vinyl chloride, composition for coating polymerization vessels and polymerization vessel coated therewith HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-26 EP disclosed
US-4189428-A DYEABILITY, COLORFASTNESS, RESISTANCE TO SUBLIMATION, IMPROVED BRIGHTNESS EASTMAN KODAK COMPANY (US) 1980-02-19 US disclosed
US-4140683-A DISPERSE DYES FOR POLYESTERS EASTMAN KODAK COMPANY (US) 1979-02-20 US disclosed
US-4049643-A DYES FOR POLYESTERS EASTMAN KODAK COMPANY (US) 1977-09-20 US disclosed