Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214528 | 0.85 | PARP10 (0.46) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL11215914 | 0.79 | PTGS1 (0.49) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL14157496 | 0.79 | RXRA (0.44) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL14122063 | 0.79 | RXRA (0.44) | RXRARXRBACHEPTGS1KMT2A | |
| Hydrochloric Acid SCHEMBL14157210 | 0.78 | RXRA (0.42) | RXRARXRBACHEPTGS1KMT2A | |
| Hydrochloric Acid SCHEMBL3698307 | 0.78 | RXRA (0.42) | RXRARXRBACHEPTGS1KMT2A | |
| Hydrochloric Acid SCHEMBL14121875 | 0.78 | RXRA (0.42) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL11213395 | 0.77 | RXRA (0.41) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL8053572 | 0.75 | RXRA (0.47) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL6055421 | 0.75 | RXRA (0.47) | RXRARXRBACHEPTGS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |