Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218410 | 0.84 | TDP1 (0.45) | TDP1ALDH1A1L3MBTL1LMNACYP3A4 | |
| SCHEMBL11215660 | 0.81 | TDP1 (0.42) | TDP1SLC1A2SLC1A1ALDH1A1L3MBTL1 | |
| SCHEMBL646907 | 0.81 | IDO1 (0.42) | CYP3A4SLC2A1FFAR4 | |
| SCHEMBL25977826 | 0.80 | ABL1 (0.36) | TDP1SLC1A2SLC1A1ALDH1A1L3MBTL1 | |
| SCHEMBL8359921 | 0.78 | TDP1 (0.50) | TDP1ALDH1A1L3MBTL1LMNACYP3A4 | |
| SCHEMBL13814427 | 0.78 | TDP1 (0.45) | TDP1ALDH1A1L3MBTL1LMNACYP3A4 | |
| SCHEMBL19251331 | 0.78 | KDM4E (0.40) | SLC1A2SLC1A1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9153345 | 0.77 | TDP1 (0.48) | TDP1ALDH1A1L3MBTL1LMNACYP3A4 | |
| SCHEMBL20374364 | 0.77 | TDP1 (0.48) | TDP1ALDH1A1L3MBTL1LMNACYP3A4 | |
| SCHEMBL3103283 | 0.77 | TDP1 (0.48) | TDP1ALDH1A1L3MBTL1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348223-A | FOR PREEMERGENT AND POSTEMERGENT APPLICATION | PPG INDUSTRIES, INC. (US) | 1982-09-07 | — | — | US | disclosed |