Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723811 | 0.82 | MCL1 (0.71) | MCL1AKR1C3AKR1C2HSD17B10KMT2A | |
| SCHEMBL2845642 | 0.78 | MCL1 (0.67) | MCL1AKR1C3AKR1C2HSD17B10KMT2A | |
| SCHEMBL3187695 | 0.78 | MCL1 (1.00) | MCL1HSD17B10KMT2AHTTHPGD | |
| SCHEMBL7207048 | 0.77 | MCL1 (0.65) | MCL1AKR1C3AKR1C2HSD17B10KMT2A | |
| SCHEMBL3978328 | 0.77 | MCL1 (0.65) | MCL1AKR1C3AKR1C2HSD17B10KMT2A | |
| SCHEMBL1285810 | 0.77 | MCL1 (0.65) | MCL1HSD17B10KMT2ATSHRHTT | |
| SCHEMBL2823587 | 0.77 | MCL1 (0.65) | MCL1AKR1C3AKR1C2HSD17B10KMT2A | |
| SCHEMBL1017987 | 0.74 | MCL1 (0.61) | MCL1AKR1C3AKR1C2KMT2ASMN1; SMN2 | |
| SCHEMBL3161431 | 0.74 | MCL1 (0.72) | MCL1AKR1C3AKR1C2HSD17B10KMT2A | |
| SCHEMBL17627402 | 0.74 | MCL1 (0.61) | MCL1AKR1C3AKR1C2HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090603-A2 | Antibacterial compounds | BEECHAM GROUP PLC (GB) | 1983-10-05 | — | — | EP | disclosed |