Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220278 | 0.85 | CYP4F2 (0.46) | KMT2AMEN1HPGDDPP4ALDH1A1 | |
| SCHEMBL23218343 | 0.82 | GAA (0.45) | EGFRKMT2AMEN1HPGDCNR2 | |
| SCHEMBL11213302 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2EGFRKMT2AMEN1HPGD | |
| SCHEMBL4717993 | 0.80 | MEN1 (0.46) | SMN1; SMN2KMT2AMEN1HPGDMAPT | |
| SCHEMBL17744510 | 0.78 | ALDH1A1 (0.40) | SMN1; SMN2HPGDMAPTALDH1A1TSHR | |
| SCHEMBL11306000 | 0.77 | HPGD (0.43) | KMT2AMEN1HPGDMAPTALDH1A1 | |
| SCHEMBL11221411 | 0.76 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AMEN1HPGDMAPT | |
| SCHEMBL11288073 | 0.75 | CYP3A4 (0.41) | KMT2AMEN1HPGDALDH1A1TSHR | |
| SCHEMBL5810846 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2EGFRKMT2AMEN1NR4A1 | |
| SCHEMBL7441541 | 0.75 | ALDH1A1 (0.50) | KMT2AMEN1HPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |