Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 5/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18622176 | 0.91 | FDPS (0.42) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL20365361 | 0.86 | CYP3A4 (0.42) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL27984266 | 0.85 | LPAR3 (0.53) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL15302820 | 0.84 | SMPD1 (0.43) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL27744277 | 0.82 | FDPS (0.41) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL2963056 | 0.79 | TSHR (0.41) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL21377374 | 0.79 | CYP3A4 (0.38) | SMPD1FDPSLAP3CYP3A4L3MBTL1 | |
| SCHEMBL26075702 | 0.77 | TSHR (0.39) | SMPD1CYP3A4L3MBTL1 | |
| SCHEMBL22404813 | 0.77 | LPAR3 (0.48) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL14746842 | 0.77 | LPAR3 (0.44) | LPAR3LPAR1LPAR2LPAR5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331545-A | FRICTION RESISTANCE IN INTERNAL COMBUSTION ENGINES | EDWIN COOPER, INC. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4325827-A | FRICTION RESISTANCE | EDWIN COOPER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| EP-0042270-A2 | Lubricating oil additive, method for making the same, lubricating oil additive package, and lubricating oil composition comprising the same, and the use of certain succinimides in forming oil additives | EDWIN COOPER INC. (US) | 1981-12-23 | — | — | EP | disclosed |
| US-4295983-A | Lubricating oil composition containing boronated N-hydroxymethyl succinimide friction reducers | ETHYL CORPORATION (US) | 1981-10-20 | — | — | US | disclosed |
| US-4293432-A | N-/2-HYDROXYETHYL/FATTY ACID AMIDE, FRICTION RESISTANCE | ETHYL CORPORATION (US) | 1981-10-06 | — | — | US | disclosed |
| US-4246125-A | ALIPHATIC HYDROCARBYL SULFINYL OR SULFONYL METHANE | EDWIN COOPER, INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4237020-A | N-ALIPHATIC HYDROCARBYL HYDROXYALKYLSULFINYLSUCCINIMIDE OR N-ALIPHATIC HYDROCARBYL HYDROXYALKYLSULFONYLSUCCINIMIDE | EDWIN COOPER, INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4225449-A | HYDROCARBYLSULFONYL OR SULFINYL ALKANOL | EDWIN COOPER, INC. (US) | 1980-09-30 | — | — | US | disclosed |