Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | FBP1 | P09467 | 3/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | TLR4 | O00206 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215148 | 1.00 | MAOB (0.55) | MAOBMAOAFBP1NR4A2ABCG2 | |
| SCHEMBL2747521 | 0.86 | FBP1 (0.62) | MAOBMAOAFBP1NR4A2TLR4 | |
| SCHEMBL2747523 | 0.86 | FBP1 (0.62) | MAOBMAOAFBP1NR4A2TLR4 | |
| SCHEMBL2747524 | 0.86 | FBP1 (0.62) | MAOBMAOAFBP1NR4A2TLR4 | |
| SCHEMBL9627326 | 0.85 | MAOB (0.58) | MAOBMAOAFBP1LMNARAB9A | |
| SCHEMBL11214795 | 0.85 | MAOB (0.58) | MAOBMAOAFBP1LMNARAB9A | |
| SCHEMBL8636871 | 0.85 | FBP1 (0.47) | MAOBMAOAFBP1TLR4TLR2 | |
| SCHEMBL9269717 | 0.83 | FBP1 (0.56) | MAOBMAOAFBP1TLR4TLR2 | |
| SCHEMBL9269719 | 0.83 | FBP1 (0.56) | MAOBMAOAFBP1TLR4TLR2 | |
| SCHEMBL15510679 | 0.83 | FBP1 (0.67) | MAOBMAOAFBP1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329367-A | ANTIHYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |