Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222163 | 0.93 | LMNA (0.47) | LMNAHTR2BPTGS1PTGS2KDM4E | |
| SCHEMBL11037931 | 0.88 | PTGS1 (0.51) | LMNAHTR2BPTGS1PTGS2KDM4E | |
| SCHEMBL11222805 | 0.83 | MAPT (0.53) | LMNAHTR2BPTGS1PTGS2KDM4E | |
| SCHEMBL11221782 | 0.83 | LMNA (0.52) | LMNAHTR2BPTGS1PTGS2KDM4E | |
| SCHEMBL11223009 | 0.82 | PTGS1 (0.62) | LMNAHTR2BPTGS1PTGS2KDM4E | |
| SCHEMBL11038921 | 0.82 | PTGS1 (0.55) | LMNAHTR2BPTGS1PTGS2KDM4E | |
| SCHEMBL9644986 | 0.81 | PTGS1 (0.53) | LMNAHTR2BPTGS1PTGS2KDM4E | |
| SCHEMBL11222276 | 0.80 | PTGS1 (0.60) | LMNAHTR2BPTGS1PTGS2KDM4E | |
| SCHEMBL10585494 | 0.80 | LMNA (0.57) | LMNAHTR2BPTGS1PTGS2KDM4E | |
| SCHEMBL11227417 | 0.80 | PTGS1 (0.67) | LMNAHTR2BPTGS1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309427-A | ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1982-01-05 | — | — | US | disclosed |