Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.72 |
| ▸ | MAPT | P10636 | 9/20 | 0.68 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11840773 | 0.91 | MAPT (0.70) | TDP1MAPTCTDSP1NR1I2HPGD | |
| SCHEMBL11444223 | 0.91 | MAPT (0.70) | TDP1MAPTCTDSP1NR1I2HPGD | |
| SCHEMBL11840763 | 0.91 | MAPT (0.70) | TDP1MAPTCTDSP1NR1I2HPGD | |
| SCHEMBL11219562 | 0.88 | MAPT (0.72) | TDP1MAPTCTDSP1NR1I2HPGD | |
| SCHEMBL11219565 | 0.88 | MAPT (0.72) | TDP1MAPTCTDSP1NR1I2HPGD | |
| SCHEMBL11502736 | 0.88 | MAPT (0.65) | TDP1MAPTCTDSP1NR1I2HPGD | |
| SCHEMBL11461975 | 0.87 | MAPT (0.71) | TDP1MAPTCTDSP1NR1I2HPGD | |
| SCHEMBL11531363 | 0.87 | MAPT (0.71) | TDP1MAPTCTDSP1NR1I2HPGD | |
| SCHEMBL11794482 | 0.86 | MAPT (0.68) | TDP1MAPTCTDSP1NR1I2HPGD | |
| SCHEMBL11503047 | 0.86 | PTGS1 (0.78) | TDP1MAPTCTDSP1NR1I2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343937-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1982-08-10 | — | — | US | disclosed |
| US-4342869-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | disclosed |
| US-4342757-A | Cephalosporin antibiotic compositions | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | disclosed |
| US-4338437-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338438-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-07-06 | — | — | US | disclosed |
| US-4324890-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1982-04-13 | — | — | US | disclosed |
| US-4297488-A | 7-α-Methoxy cephalosporins | MERCK & CO., INC. (US) | 1981-10-27 | — | — | US | disclosed |
| US-4107432-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4058661-A | 7-Diacyl cephalosporins | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | disclosed |