Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215432 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL4860394 | 0.89 | KMT2A (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL4860402 | 0.89 | KMT2A (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5982549 | 0.88 | MAPT (0.48) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5982543 | 0.88 | MAPT (0.48) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL4863994 | 0.87 | KMT2A (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL4863455 | 0.87 | KMT2A (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11217306 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1KMT2ATTR | |
| SCHEMBL11217309 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1KMT2ATTR | |
| SCHEMBL2436417 | 0.83 | MEN1 (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |