Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516521 | 0.81 | MGLL (0.39) | MGLLFAAHPTGS1PTGS2ALOX5 | |
| SCHEMBL7741932 | 0.68 | GAA (0.37) | MGLLFAAHPTGS1PTGS2ALOX5 | |
| SCHEMBL17767287 | 0.67 | MGLL (0.42) | MGLLFAAHPTGS1PTGS2ALOX5 | |
| SCHEMBL5505943 | 0.65 | MGLL (0.45) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL11499488 | 0.65 | MGLL (0.50) | MGLLFAAHPTGS1PTGS2ALOX5 | |
| SCHEMBL13837373 | 0.65 | MGLL (0.46) | MGLLFAAHPTGS1PTGS2ALOX5 | |
| SCHEMBL162838 | 0.65 | MGLL (0.46) | MGLLFAAHPTGS1PTGS2ALOX5 | |
| SCHEMBL2037670 | 0.65 | — | — | |
| SCHEMBL2991298 | 0.63 | MGLL (0.47) | MGLLFAAHPTGS1PTGS2ALOX5 | |
| SCHEMBL3420576 | 0.63 | KMT2A (0.56) | MGLLFAAHPTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085291-A1 | 2-Oxo-1-(aminocarbonylaminosulfonylaminocarbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1983-08-10 | — | — | EP | disclosed |