⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936329 | 0.72 | — | — | |
| SCHEMBL5936336 | 0.72 | — | — | |
| SCHEMBL28216706 | 0.70 | — | — | |
| SCHEMBL15080603 | 0.67 | — | — | |
| SCHEMBL8206079 | 0.65 | — | — | |
| SCHEMBL12184005 | 0.65 | — | — | |
| SCHEMBL5936335 | 0.63 | ALDH1A1 (0.42) | — | |
| SCHEMBL17993550 | 0.61 | — | — | |
| SCHEMBL7852931 | 0.60 | — | — | |
| SCHEMBL8237088 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118638104-A | Synthesis and application of indolone lactone analogue with oxime ether linkage | 南开大学 | 2024-09-13 | — | — | CN | disclosed |
| EP-3693362-B1 | PARASITIC PLANT GERMINATION REGULATOR | NATIONAL UNIV CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2023-12-20 | — | — | EP | disclosed |
| CN-114369087-B | Synthesis and application of lactone analogue with indoline-2-ketone skeleton | 南开大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-114369087-A | Synthesis and application of lactone analogue with indoline-2-ketone skeleton | 南开大学 | 2022-04-19 | — | — | CN | disclosed |
| EP-3693362-A1 | PARASITIC PLANT GERMINATION REGULATOR | National University Corporation Nagoya University (JP) | 2020-08-12 | — | — | EP | disclosed |
| EP-0075680-A1 | Substituted furanones and process for preparing 3,4-dihydro-alpha-pyrones and substituted furanones | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1983-04-06 | — | — | EP | disclosed |