Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL11124939 | 0.87 | POLB (0.41) | CHRM2CHRM1MEN1KMT2APOLB | |
| SCHEMBL5483785 | 0.84 | CHRNB2 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4POLB | |
| SCHEMBL27717164 | 0.81 | PARP1 (0.45) | CHRM2CHRM1CHRM3PARP1 | |
| SCHEMBL27722775 | 0.81 | PARP1 (0.45) | CHRM2CHRM1CHRM3PARP1 | |
| SCHEMBL27810023 | 0.80 | CHRM2 (0.38) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL28060573 | 0.79 | CHRM2 (0.37) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3521419 | 0.73 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4POLB | |
| SCHEMBL747476 | 0.73 | DPP4 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4POLB | |
| SCHEMBL2321580 | 0.73 | DPP4 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4POLB | |
| SCHEMBL745860 | 0.73 | DPP4 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077720-A1 | Biphenyl alkyl carboxylated derivatives, process for their preparation and their use as medicines | PIERRE FABRE S.A. (FR) | 1983-04-27 | — | — | EP | disclosed |