Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TARBP2 | Q15633 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215881 | 0.84 | ALDH1A1 (0.36) | HPGDKDM4ETARBP2HTTCYP1A2 | |
| SCHEMBL16571753 | 0.80 | HTT (0.48) | HPGDTARBP2HTTALDH1A1LMNA | |
| SCHEMBL23990453 | 0.80 | CYP1A2 (0.42) | HPGDKDM4ETARBP2HTTCYP1A2 | |
| SCHEMBL23989838 | 0.77 | MAPT (0.44) | HPGDKDM4ETARBP2HTTCYP1A2 | |
| SCHEMBL6873803 | 0.75 | HPGD (0.43) | HPGDKDM4ETARBP2HTTCYP1A2 | |
| SCHEMBL18490147 | 0.74 | CYP1A2 (0.37) | HPGDKDM4ETARBP2HTTCYP1A2 | |
| SCHEMBL23990463 | 0.74 | CYP1A2 (0.37) | HPGDKDM4ETARBP2HTTCYP1A2 | |
| SCHEMBL8920076 | 0.73 | CA12 (0.46) | HPGDKDM4ETARBP2HTTCYP1A2 | |
| SCHEMBL23991189 | 0.73 | CYP1A2 (0.36) | HPGDKDM4ETARBP2HTTCYP1A2 | |
| SCHEMBL18490196 | 0.72 | PDE4B (0.38) | HPGDKDM4EALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57118594-A | — | — | None | — | — | JP | disclosed |
| JP-S57118594-A | ISOXAZOLE, ITS PREPARATION AND INSECTICIDE, ACARICIDE AND NEMATOCIDE CONTAINING THE SAME AS ACTIVE CONSTITUENT | SUMITOMO CHEM CO LTD | 1982-07-23 | — | — | JP | disclosed |