Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1130097 | 0.77 | TSHR (0.50) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL28416835 | 0.75 | TSHR (0.59) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1218125 | 0.74 | — | — | |
| SCHEMBL4217261 | 0.73 | SMN1; SMN2 (0.54) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL3236704 | 0.72 | TSHR (0.54) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL28359120 | 0.72 | TSHR (0.39) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL28362812 | 0.72 | TSHR (0.39) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9131970 | 0.72 | — | — | |
| SCHEMBL1345524 | 0.72 | — | — | |
| SCHEMBL1022556 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57000181-A | — | — | None | — | — | JP | disclosed |
| JP-S57181-A | INSULATION PAINT | NITTO ELECTRIC IND CO LTD | 1982-01-05 | — | — | JP | disclosed |